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Uncaria tomentosa (Rubiaceae)

Botanical Information

Family: Rubiaceae
Common Names: Cat’s Claw, Uña de Gato, Hawk’s Claw
Parts Used: Bark, Root, Leaves

Description

Uncaria tomentosa, commonly known as Cat’s Claw, is a woody vine native to the Amazon rainforest and other tropical regions of South America. It is highly valued in traditional herbal medicine, particularly by Indigenous Amazonian tribes, for its immune-modulating, anti-inflammatory, and antiviral properties. This herb is best known for its use in treating chronic inflammatory diseases, autoimmune disorders, and infections. The bark and root contain potent alkaloids that have immunostimulant and adaptogenic effects, making it beneficial for immune support, joint health, and digestive function.


Historical and Traditional Uses

  • Used by Indigenous Amazonian tribes for treating infections, inflammation, digestive disorders, and joint pain.
  • Traditionally applied as an immune booster to help fight viral and bacterial infections.
  • Employed as a general tonic for chronic fatigue, arthritis, and digestive inflammation.
  • Historically used to promote wound healing and detoxify the blood.

Constituents

  • Alkaloids (Isopteropodine, Pteropodine, Rhynchophylline)
  • Glycosides
  • Flavonoids
  • Tannins
  • Sterols (Beta-sitosterol)

Actions

  • Immunomodulator
  • Anti-inflammatory
  • Antiviral
  • Antioxidant
  • Adaptogenic
  • Antimicrobial
  • Anti-rheumatic

Medicinal Uses

  1. Immune System Support
    • Stimulates white blood cell activity, enhancing immune defense.
    • Used in chronic viral infections, such as herpes, HIV, and Epstein-Barr virus.
  2. Autoimmune & Inflammatory Disorders
    • Modulates the immune system, helping with rheumatoid arthritis, lupus, and multiple sclerosis.
    • Reduces chronic inflammation in the joints, gut, and nervous system.
  3. Joint & Musculoskeletal Health
    • Traditionally used to relieve arthritis, osteoarthritis, and fibromyalgia symptoms.
    • Supports joint mobility and reduces stiffness.
  4. Digestive & Gut Healing
    • Used for gastritis, leaky gut syndrome, and inflammatory bowel diseases (IBD).
    • Promotes gut flora balance and helps reduce intestinal inflammation.
  5. Antiviral & Antimicrobial Effects
    • Effective against viral, bacterial, and fungal infections.
    • Traditionally used in respiratory infections, chronic Lyme disease, and urinary tract infections (UTIs).

Preparation and Dosage

Decoction (Tea from Bark or Root):

  • 1-2 tsp of dried bark per cup of water.
  • Simmer for 20-30 minutes, drink up to twice daily.

Tincture:

  • 2-5 ml taken up to twice daily.

Capsules (Standardized Extract):

  • 300-500 mg per day, or as directed by a practitioner.

Precautions and Contraindications

  • Pregnancy & Breastfeeding: Avoid use, as it may affect immune function and uterine contractions.
  • Autoimmune Conditions: May over-stimulate the immune system in some individuals—use with caution.
  • Blood Thinners & Surgery: Has blood-thinning properties—avoid before surgery or if on anticoagulants.
  • Low Blood Pressure: May lower blood pressure, so use with caution if prone to hypotension.

Energetics (Traditional Medicine Perspectives)

Traditional Amazonian Medicine: Used for immune support, wound healing, and inflammation reduction.
Traditional Western Herbalism: Cooling and drying; helps clear heat and inflammation while strengthening immunity.


Combinations

  • For Autoimmune Support: Combine with turmeric, ashwagandha, and boswellia.
  • For Viral Infections: Use with elderberry, astragalus, and licorice root.
  • For Joint Health: Pair with devil’s claw and white willow bark.
  • For Digestive Healing: Blend with slippery elm and marshmallow root.

Harvesting and Storage

  • Harvesting:
    • Sustainably harvested bark and root are preferred.
  • Drying:
    • Air dry in a shaded, well-ventilated area.
  • Storage:
    • Keep in airtight containers, away from moisture and heat.

Modern Research

  • Studies confirm Uncaria tomentosa’s immunomodulating, anti-inflammatory, and antioxidant properties.
  • Research suggests its alkaloid content helps regulate immune function and reduce inflammation.
  • Clinical trials indicate benefits for arthritis, viral infections, and digestive disorders.

Conclusion

Uncaria tomentosa is a powerful adaptogenic and immune-supportive herb, traditionally used for chronic inflammation, autoimmune conditions, and infections. While beneficial, it should be used with caution in autoimmune diseases and alongside blood-thinning medications.